Modulation of Adjuvant Arthritis by Cellular and Humoral Immunity to Hsp65

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Modulation of Adjuvant Arthritis by Cellular and Humoral Immunity to Hsp65

Heat shock proteins (Hsps) are highly conserved, and their expression is upregulated in cells by heat and other stressful stimuli. These proteins play a vital role in preserving the structural and functional integrity of cells under stress. Despite the ubiquitous expression of Hsps in an individual, the immune system is not fully tolerant to them. In fact, Hsps are highly immunogenic in nature,...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2016

ISSN: 1664-3224

DOI: 10.3389/fimmu.2016.00203